Biofilm Engineering and Drug Discovery Laboratory

Research

Current work and collaborative research projects include (i) the investigation of the impact of biofilm structural features (i.e., porosity, diffusional distance, biomass, and biovolume) and physical fluid forces on the efficacy of known antimicrobial agents; (ii) the evaluation of potential antimicrobial challenge mechanisms as a strategy for in situ biofilm control; and (iii) the identification of novel chemical probes and microbial targets and development of novel drug delivery strategies in biofilm settings.

Selected 2018 Research

BEDD Research at 2018 Howard University Research Symposium
Research from the Biofilm Engineering and Drug Discovery (BEDD) group was featured at the 2018 Howard University Research Symposium (April 9-13) in Washington, DC. Our students and post-doctoral fellow proudly presented their research effort in oral and poster sessions:

Marlon Brutus * (Senior undergraduate student in Chemical Engineering): “An Analytical Method to Study the Effect of Fluid Shear Rates and Media Strength on Kinetics of Biofilm Formation” (Poster).
Tafadzwa Chigumira ** (Graduate student in Chemical Engineering): “Microbial Reduction of Iodate for Bioremediation at the Hanford Site”.
Elbethel Damtae * (Graduate student in Chemical Engineering): “A Microfluidic Approach for the Analysis of Small-Molecule Compounds Modulating Bacterial Biofilm Formation” (Poster)
Ayomikun Olarinoye ** (Junior undergraduate student in Chemical Engineering): “Evaluating the Activity of Community 31 Bacteria from the Hanford Site in the Bioremediation of Iodate” (Poster).
Jyothirmai Simhadri ** (Post-doctoral fellow): “Development of Shewanella oneidensis MR-1 Biofilms for Iodate Reduction in Groundwater” (Poster).
Mahtab Waseem * (Senior undergraduate student in Chemical Engineering): “A Small-Molecule Compound Modulating Bacterial Biofilm Formation by Vibrio cholerae and Staphylococcus aureus”.

(*) Projects funded by the National Science Foundation (NSF Award Number: 1505301).

(**) Projects funded by the Department of Energy’s Minority Serving Institutions Partnership (MSIPP) at Savannah River National Laboratory.

BEDD Research featured at 2018 ERN Conference in STEM
Research from the Biofilm Engineering and Drug Discovery (BEDD) group was featured at the Emerging Researchers National Conference (ERN) in Science, Technology, Engineering and Mathematics (STEM) in Washington, DC. The ERN conference was held at the Washington Marriott Wardman Park hotel on February 22-24, 2018.

Mahtab Waseem (a senior undergraduate student in Chemical Engineering) presented a poster titled: “Chemical Screen of Chemical Compound Modulators of the Vibrio cholerae PTS and Biofilm Formation.” This work was funded by the National Science Foundation (NSF Award Number: 1505301).

Research Recognition

Collaborators:

  • Oladapo Bakare, Ph.D. (Department of Chemistry, Howard University)
  • Legand L. Burge, III, Ph.D. (Department of Systems & Computer Science, Howard University)
  • Preethi L. Chandran, Ph.D. (Department of Chemical Engineering, Howard University)
  • Kimberly L. Jones, Ph.D. (Department of Civil & Environmental Engineering, Howard University)
  • Michael Lipscomb, Ph.D. (Department of Biology, Howard University)
  • Karl M. Thompson, Ph.D. (Department of Microbiology, College of Medicine, Howard University)
  • Julia Ross, Ph.D. (Department of Chemical, Biochemical & Environmental Engineering, UMBC)
  • Paula Watnick, MD, Ph.D. (Division of Infectious Diseases, Boston Children’s Hospital, & Department of Pediatrics, Harvard Medical School)
  • Patrick Still, Ph.D. (Department of Chemistry, California State University, Dominguez Hills)

Notable Student Awards:

  • Simone Stanley:
    • 1st Place award at the Undergraduate Student Poster Competition [General Engineering and Engineering Education Session] at the 2016 AIChE Annual Meeting in San Francisco, LA
  • Mahtab Waseem:
    • 3rd Place award for her presentation at the 2017 ERN Conference in Washington, D.C.
    • 2nd Place award at the Undergraduate Student Poster Competition of the North Central Branch ASM 2016 Meeting held at Iowa State University
    • 1st Place award at the 2016 Washington Baltimore Hampton Roads-Louis Stokes Alliance for Minority Participation (WBHR-LSAMP)
    • 3rd Place award at the Undergraduate Student Poster Competition [Food, Pharmaceutical, and Biotechnology Session IX] of the 2015 AIChE Annual Meeting in Salt Lake City, UT

Other Awards:

  • Dr. Jyothirmai Simhadri (Post-Doc):
    • 1st Place award at the 2018 Howard University Research Symposium in Washington, D.C.

News

Thomas Brings Home a Win from 2018 Annual AIChE Meeting

Mon, December 10, 2018

Chemical Engineering Junior Jamaka Thomas won second place in the Food, Pharmaceutical and Biotechnology category at the 2018 Annual AIChE Meeting for her research submission titled: “Enrichment of Oat Protein by Means of Gravity and Electrostatic Forces.” Thomas co-authored her submission with Chemical Engineering Graduate Student Dinara Konakbayeva.Read More >>

Assistant Professor Patrick Ymele-Leki Mentors Postdoctoral Researcher and 2018 Research Week Winner

Fri, April 20, 2018

Chemical Engineering postdoctoral researcher Jyothirmai Simhadri was announced as the Post Doc/Resident/Fellow/Research Associate winner in the Physical Sciences and Engineering category for her research submission titled: "Development of Shewanella Oneidensis MR-1 Biofilms for Iodate Reduction in Groundwater". Read More >>

Events

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