Biofilm Engineering and Drug Discovery Laboratory (BEDD)

Research

Our long-term goal is to enhance current antimicrobial arsenal and further understanding of complex microbial communities. Our research program focuses on (i) the development and implementation of high‐ and low- throughput screening assays for the identification of novel small molecules with antimicrobial activity, (ii) the development and characterization of physiologically and industrially relevant multispecies in vitro biofilm models for the identification of potential drug targets, and (iii) the in vivo assessment of cytotoxicity and pharmacokinetics parameters and hypothesis‐driven validation of antimicrobial drug targets for site colonization related to biofilm formation. This approach combines the benefits of physiologically and industrially relevant assays with a target validation approach superior to that typically encountered for either drug discovery screening or biofilm resistance studies.

More information on research projects.

People

Our current research team comprises the diverse and multidisciplinary expertise of professors, graduate and undergraduate students. More information on team members.

Publications

BEDD has published peer-reviewed maunscripts in several chemical engineering and other scientific journals. More information on research publications.

News

Thomas Brings Home a Win from 2018 Annual AIChE Meeting

Mon, December 10, 2018

Chemical Engineering Junior Jamaka Thomas won second place in the Food, Pharmaceutical and Biotechnology category at the 2018 Annual AIChE Meeting for her research submission titled: “Enrichment of Oat Protein by Means of Gravity and Electrostatic Forces.” Thomas co-authored her submission with Chemical Engineering Graduate Student Dinara Konakbayeva.Read More >>

Assistant Professor Patrick Ymele-Leki Mentors Postdoctoral Researcher and 2018 Research Week Winner

Fri, April 20, 2018

Chemical Engineering postdoctoral researcher Jyothirmai Simhadri was announced as the Post Doc/Resident/Fellow/Research Associate winner in the Physical Sciences and Engineering category for her research submission titled: "Development of Shewanella Oneidensis MR-1 Biofilms for Iodate Reduction in Groundwater". Read More >>

Events

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