Biofilm Engineering and Drug Discovery Laboratory (BEDD)

Research

Our long-term goal is to enhance current antimicrobial arsenal and further understanding of complex microbial communities. Our research program focuses on (i) the development and implementation of high‐ and low- throughput screening assays for the identification of novel small molecules with antimicrobial activity, (ii) the development and characterization of physiologically and industrially relevant multispecies in vitro biofilm models for the identification of potential drug targets, and (iii) the in vivo assessment of cytotoxicity and pharmacokinetics parameters and hypothesis‐driven validation of antimicrobial drug targets for site colonization related to biofilm formation. This approach combines the benefits of physiologically and industrially relevant assays with a target validation approach superior to that typically encountered for either drug discovery screening or biofilm resistance studies.

More information on research projects.

People

Our current research team comprises the diverse and multidisciplinary expertise of professors, graduate and undergraduate students. More information on team members.

Publications

BEDD has published peer-reviewed maunscripts in several chemical engineering and other scientific journals. More information on research publications.

News

Associate Professor Preethi Chandran Awarded $500K NSF Grant for Biological Research

Tue, September 29, 2020

Chemical Engineering Associate Professor and Director of Graduate Studies Preethi Chandran, Ph.D., received a $500K grant from the National Science Foundation (NSF) through the Excellence in Research (EiR) program to study the biophysics of the shield of sugars (glycans) that typically covers pathogens.Read More >>

Associate Professor Preethi Chandran Partners with Heart of Tabitha Foundation on STEM and College Readiness Workshop

Fri, September 11, 2020

The Heart of Tabitha Foundation partnered with Howard University Chemical Engineering Associate Professor and Director of Graduate Studies Preethi Chandran, Ph.D., and Catholic University Biomedical Engineering Associate Professor Otto Wilson, Ph.D., to continue offering its annual summer workshop for local high school students in a virtual setting. The workshop focused on college readiness and STEM careers and featured speakers from several professions. Read More >>

Events

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